Urology Clinical Trials Update: Week 45, 2026

Published November 6, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

Effect of Oxybutynin on Opioid Use After Urologic Surgery in Children

This study is exploring whether giving children oxybutynin before urologic surgery can help reduce their need for opioid pain medications afterward. If this approach works, it could mean children experience better pain control with less exposure to opioids, which have a risk of side effects and addiction. The trial is currently enrolling 200 children in Canada undergoing surgeries for conditions like ureteropelvic junction obstruction and hypospadias.

The Application of Somatosensory Interactive Pelvic Floor Muscle Training for Stress Urinary Incontinence in Men Underwent Radical Prostatectomy

This research is testing new pelvic floor muscle training methods for men who have urinary leakage after prostate cancer surgery. The goal is to find more effective, non-invasive exercises that improve bladder control and enhance quality of life following prostate removal. The study is recruiting 100 men in China and Hong Kong and uses interactive techniques to guide muscle training.

Performance, Feasibility, and Safety Study for a Novel Endoluminal Robotic System for En-Bloc Resection of Bladder Tumours: First-In-Human Trial

This trial is evaluating a new robotic system designed to remove bladder tumors in one piece, which may offer more precise and safer surgery for bladder cancer patients. If successful, this technology could improve surgical outcomes and reduce complications compared to current methods. The small initial study is recruiting participants in Hong Kong.

Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy

This study is comparing two surgical approaches for men with bladder cancer undergoing removal of the bladder, focusing on whether preserving the prostate capsule helps maintain sexual and urinary function. Researchers want to see if this approach can improve quality of life without increasing cancer risks. The trial is enrolling 70 men in the United States.

Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)

This research is testing the safety and effectiveness of the Medtronic Hugo robotic system for a range of urologic surgeries, including procedures for bladder, prostate, and kidney cancers, as well as other pelvic conditions. Using robotic assistance may reduce invasiveness and complications during surgery. The study includes 144 participants in the United States and is actively ongoing but not currently recruiting.

This week in urology research, there is notable progress in improving surgical techniques and postoperative care. Studies are focusing on reducing opioid use in children, enhancing recovery after prostate surgery, and advancing robotic surgery options for bladder and other urologic cancers. These developments hold promise for safer surgeries and better quality of life for patients. Continued research and patient participation will be key to turning these innovations into standard care.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.