Urology Clinical Trials Update: Week 44, 2026

Published October 30, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

Effect of Intravesical B.C.G and Gemcitabine on Semen Analysis and Testicular Volume in NMIBC

This completed study from Egypt looked at how bladder cancer treatments using B.C.G and gemcitabine affect semen quality and testicular size in men with non-muscle invasive bladder cancer. Understanding these effects is important for patients concerned about fertility and testicular health during cancer treatment. The results provide helpful information on how local bladder therapies might impact reproductive function.

EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENT THERAPY IN CHILDREN WITH SPINAL DYSRAPHISM

This ongoing study in France is testing a new adjustable balloon device implanted to help children with neurogenic bladder caused by spinal dysraphism manage urinary incontinence. If successful, this device could offer a less invasive way to improve bladder control in children who struggle with current treatment options. The trial includes school-age children and aims to improve their quality of life by reducing urinary accidents.

EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENCE THERAPY BALLOONS IN BLADDER EXSTROPHY AND INCONTINENT EPISPADIAS PATIENTS

Also conducted in France, this study is testing adjustable continence therapy balloons as a new surgical option for children with bladder exstrophy or epispadias who experience urinary incontinence. By using a less invasive approach than traditional surgeries, this treatment could reduce recovery time and improve bladder control. The trial is currently active but not recruiting, focusing on a small group of patients.

Feasibility of Resisted Expiratory Muscle Training for Females Assigned at Birth With Stress Urinary Incontinence: A Pilot Study

This pilot study at Thomas Jefferson University is exploring whether adding breathing muscle exercises to standard pelvic floor therapy can better help women with stress urinary incontinence. The study involves weekly sessions over six weeks to see if this combined approach improves muscle strength and reduces leakage more than pelvic floor exercises alone. This research could lead to improved non-surgical treatment options.

Prostatic Artery Embolization Using Histoacryl as a Novel Embolizing Agent for Treatment of BPH

This study from Assiut University is testing a new minimally invasive treatment using Histoacryl glue to block blood flow in the prostate for men with benign prostatic hyperplasia who have not responded to medication. If effective, this procedure could provide a quicker and possibly safer alternative to existing therapies for improving urinary symptoms. The trial plans to follow 30 men for three months after treatment.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.