Urology Clinical Trials Update: Week 26, 2026

Published June 26, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

Prevention of Urinary Stones With Hydration

This completed trial by Duke University studied whether drinking more fluids can help prevent urinary stones from coming back in both adults and children. The results, collected from multiple locations in the United States, suggest that increasing hydration could be a simple and non-invasive way to reduce the risk of painful stone episodes. For patients who have experienced urinary stones, this approach offers a potentially easy lifestyle change to lower the chance of recurrence.

Infective Complications in TP Biopsy Without Antibiotic Prophylaxis

Completed at the Chinese University of Hong Kong, this study looked at the safety of performing transperineal prostate biopsies without using antibiotics beforehand. The goal was to see if this method could reduce antibiotic use and its side effects while still being safe for men undergoing prostate cancer diagnosis. Although results have not yet been published, the trial involving over 1700 men may lead to simpler biopsy procedures with fewer medications.

STEAM-MAP 1 Study - Steam Therapy With MRI and AI-assisted Planning

Currently recruiting in Hong Kong, this study explores a new treatment for men with benign prostatic hyperplasia or BPH, which is prostate enlargement. The therapy uses MRI and ultrasound fusion with steam to target the prostate more precisely. This advanced method aims to improve symptom relief with a minimally invasive procedure, offering hope for better management of urinary symptoms caused by BPH.

Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery

This trial from Jagiellonian University in Poland is testing opioid-free anesthesia during urological surgeries. By avoiding opioids, the study hopes to reduce the common side effects linked to these pain medications and improve recovery after surgery. About 600 patients are being followed for 24 hours after their procedures to see if this approach can offer safer pain control.

The Impact of a Web-based Empowerment Program on Intolerance of Uncertainty and Maintenance Burden

This upcoming study plans to enroll caregivers of prostate cancer patients to test a web-based program designed to help them manage stress and uncertainty. Caregiving can be emotionally demanding, and this program aims to provide tools that reduce the burden and improve coping. If successful, it could become a valuable resource for families supporting loved ones with prostate cancer.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.