Urology Clinical Trials Update: Week 23, 2026

Published June 5, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

CYTALUX™for the Intraoperative Imaging of Prostate Cancer

This Phase 2 study from Indiana University tested a new fluorescent imaging agent called Cytalux™ during prostate cancer surgery. Cytalux™ helps surgeons see cancerous tissue more clearly while operating, which may improve the chances of removing all cancer cells. The trial completed with 9 participants in the United States, and results are expected to show whether this approach can reduce cancer recurrence after surgery.

Intravesical Aminophylline to Facilitate Ureteroscopic Access in Children With Distal Ureteral Stones

This Phase 2 trial in Egypt is exploring the use of intravesical aminophylline to help children with distal ureteral stones get easier access for ureteroscopy, a common procedure to treat these stones. If successful, this method could reduce the need for more invasive treatments and improve the chances of successfully removing stones in a single operation. The study is currently recruiting children who have difficulty with initial ureteroscopic access.

Noninvasive Urine Testing for Urothelial Carcinoma

Researchers in China are conducting a large study to evaluate new noninvasive urine tests for detecting urothelial carcinoma, which includes bladder and upper urinary tract cancers. This testing method aims to provide a simpler and less invasive way to diagnose these cancers, especially in adults who have blood in their urine. The trial hopes to enroll up to 800 participants and could lead to earlier and easier cancer detection.

CUIMC Focal Therapy Registry

Columbia University is collecting information on patients with prostate cancer who are receiving focal therapies such as high intensity focused ultrasound or irreversible electroporation. These treatments target only the cancerous part of the prostate rather than the entire gland. This registry aims to better understand how well these therapies work and their effects, which could improve treatment choices for prostate cancer patients. The study plans to include up to 1000 patients.

Analgesic Efficacy of Ultrasound-guided External Oblique Intercostal Plane Block Versus Posterior Transversus Abdominis Plane Block in Patients Undergoing Open Nephrectomy

This study from Cairo University is comparing two types of ultrasound-guided nerve blocks to manage pain after open nephrectomy surgery for kidney cancer. Finding effective pain relief methods can help reduce the need for opioids, leading to safer recovery experiences. The trial is recruiting adults undergoing this surgery and aims to identify the best approach to control postoperative pain.

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