Urology Clinical Trials Update: Week 16, 2026

Published April 17, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert

Efficacy and Safety of Circumcision Alone on Risk of Febrile Urinary Tract Infections in Boys With Posterior Urethral Valves: a Prospective Randomized Open-label Multicentric Trial Enriched With Historic Controls

This Phase 2 trial is exploring whether circumcision by itself can reduce the risk of serious urinary tract infections in boys with a condition called posterior urethral valves. If circumcision alone is found to be as effective as circumcision combined with antibiotics, it could simplify treatment and reduce the need for medications in these young patients. The study is currently recruiting 72 boys in France.

A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer

This early-stage trial is testing a new treatment called Belzupacap Sarotalocan (AU-011) for people with non-muscle-invasive bladder cancer. The approach uses a combination of injections and laser therapy to target tumors directly, which might improve safety and effectiveness compared to current options. Up to 55 participants are being recruited in the United States and Australia.

Concomitant Trans-Perineal Prostate Biopsy and Ablation (Bioblation) for Prostate Cancer

This study is examining a combined procedure that performs a prostate biopsy and laser ablation at the same time for men with prostate cancer and lower urinary tract symptoms. The goal is to offer faster relief from symptoms and reduce the number of procedures patients need. The trial is recruiting adults with symptomatic prostate conditions in Egypt.

Measuring Surgical Recovery After Radical Cystectomy

This observational study is gathering detailed information about recovery after radical cystectomy, a major surgery for bladder cancer. By understanding how patients recover, the study aims to improve care and support for future patients undergoing this operation. Recruitment is ongoing at multiple sites in the United States.

Effect of a Probiotic on the Urinary Tract Microbiota of Participants With Recurrent Urinary Tract Infection

This study is testing whether a probiotic can change the urinary tract bacteria in women who often get urinary tract infections. If successful, the probiotic could offer a new way to reduce infections without relying on antibiotics. The trial lasts about six and a half months and is recruiting participants in Spain.

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