Urology Clinical Trials Update: Week 14, 2026

Published April 3, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert

Topical Steroids to Prevent Recurrent Urinary Tract Infections in Uncircumcised Male Infants: a Pilot Study

This Phase 4 trial sponsored by Baylor College of Medicine is testing a topical steroid cream to help prevent repeat urinary tract infections in uncircumcised male infants. The treatment involves applying the cream twice a week for four weeks, with follow-up visits to monitor results. If successful, this approach could offer a non-surgical way to lower the chance of infections in young boys, potentially reducing discomfort and the need for antibiotics.

Quality of Life After Treatment for Bladder Cancer: The Bladder Cancer Survivorship Study

Conducted by the Mayo Clinic, this study looks at how treatments for early to mid-stage bladder cancer affect patients’ quality of life. By understanding the challenges survivors face after treatment, this research aims to improve support and care for people living beyond bladder cancer. The study includes a wide range of bladder cancer stages and is currently recruiting in the United States.

Fusion Guided Focal Laser Ablation of Prostate Cancer

The National Institutes of Health Clinical Center is exploring a new ultrasound-guided laser treatment for men with localized prostate cancer. This less invasive technique targets prostate tumors visible on MRI, potentially offering a more precise and comfortable alternative to traditional treatments. The study is open to men aged 18 and older in the United States.

Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALA

This Phase 2 trial led by Henry Ford Health System is testing a special imaging method to help surgeons better see and remove upper tract urothelial carcinoma tumors. The technique uses a fluorescent dye called 5-ALA during endoscopy, which could improve tumor detection and surgical outcomes. Patients undergoing ureteroscopic tumor removal in the United States are eligible to participate.

Shear Wave Elastography for Predicting Extracorporeal Shock Wave Lithotripsy Outcomes in Pediatric Renal Stones

Researchers at Beni-Suef University in Egypt are studying a new ultrasound technique called shear wave elastography to predict how well children with kidney stones will respond to shock wave treatment. This method may help doctors plan treatments better while reducing the need for radiation exposure. Patients will be followed for three months after treatment to assess success.

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