Urology Clinical Trials Update: Week 13, 2026

Published March 29, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer

This phase III trial is exploring whether new strains of BCG vaccine therapy can better prevent the return of high-grade non-muscle invasive bladder cancer. Patients who have not previously received BCG treatment are being enrolled across the United States. The study’s results could lead to improved options for reducing cancer recurrence in this early bladder cancer group.

New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia

This Phase 2b trial is testing new oral combination treatments for men with benign prostatic hyperplasia, a common condition causing urinary symptoms. The study focuses on patients who do not respond well to current medicines, aiming to find better ways to ease symptoms and improve quality of life. It is currently recruiting at one site in the United States and will assess outcomes after one year.

Neoadjuvant Chemotherapy Before Surgery vs Surgery Alone for UTUC: A Randomized Trial

This Phase 2 trial in China is evaluating whether giving chemotherapy before surgery can improve outcomes for patients with high-risk upper tract urothelial carcinoma. Researchers hope that chemotherapy before surgery will shrink tumors and increase survival compared to surgery alone. Although the study is not recruiting, its findings will help guide future treatment choices for this rare type of urinary tract cancer.

Surface Electrical Stimulation for Urinary Incontinence in Men Treated for Prostate Cancer

This Phase II study is testing a device called Elidah that uses electrical stimulation to reduce urinary incontinence in men after prostate cancer treatment. If effective, this device could provide a non-drug option to help men manage urinary leakage and improve daily life. The trial is currently enrolling participants in the United States and involves daily use of the device at home for six weeks.

Home Semen Testing in Men Beginning Attempts to Conceive

This completed study evaluated a home semen testing device for men starting to try for a baby, aiming to detect infertility issues early. The goal is to reduce anxiety and speed up diagnosis and treatment, which could improve fertility chances and lower healthcare costs. The study included 200 participants and was conducted in the United States.

The field of urology continues to see active research focused on improving treatments for bladder cancer, prostate conditions, and urinary symptoms. Ongoing trials are testing new drug combinations, innovative devices, and approaches that could enhance patient care and quality of life. More results are expected in the coming months to guide future options for patients and caregivers.

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