Autoimmune & Rheumatology Clinical Trials Update: Week 32, 2026

Published August 7, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

A Study of the Efficacy and Safety of SHR-1314 for Adult Active Psoriatic Arthritis

This Phase III trial is testing a new injection called SHR-1314 for adults with active psoriatic arthritis, a condition that causes joint pain and swelling. If this treatment works well, it could provide a new way to reduce joint inflammation and help improve quality of life for patients. The study is currently recruiting in China and includes a 24-week treatment period followed by monitoring to track safety and benefits.

TLL-018 in Patients With Moderate to Severe Active Rheumatoid Arthritis With Inadequate Response or Intolerance to csDMARDs

This Phase II study is exploring a drug named TLL-018 for people with moderate to severe rheumatoid arthritis who have not had success with or cannot tolerate standard treatments. The goal is to find a new option that might better control symptoms like joint pain and swelling. Although the trial is not recruiting right now, it plans to enroll about 90 participants in China to evaluate the drug’s effects.

A Clinical Study of ACG102 Injection in Patients With Refractory Active Systemic Lupus Erythematosus

This early phase 1 trial is testing ACG102, an intravenous injection, in patients with a difficult-to-treat form of systemic lupus erythematosus (SLE). The study aims to determine if this new treatment is safe and shows signs of effectiveness for people who have not responded to current therapies. The trial is small and has not started recruiting yet, with results expected after initial safety checks.

TMJ Arthroscopy Compared to Arthrocentesis in Disc Displacement Without Reduction

This study compares two types of surgery for people experiencing jaw pain from temporomandibular joint disc displacement without reduction. It seeks to find which surgery better improves jaw movement and reduces pain and disability. The trial is recruiting in Sweden and will follow patients for two years after surgery to see long-term results.

Using Personalized Rehabilitation to Reduce Disease and Increase Activity of Patients With Polymyalgia Rheumatica

This study is testing a personalized rehabilitation program called Movement Pattern Training for patients with polymyalgia rheumatica, a condition that causes joint stiffness and pain. The program aims to reduce pain, help patients be more active in daily life, and possibly reduce the need for medications. The trial is small and not yet recruiting, with results expected to help design larger future studies.

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