Lung & Respiratory Disease Clinical Trials Update: Week 17, 2026

Published April 24, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

Trial of an AI-enabled Digital Stethoscope to Improve Antibiotic Stewardship

This Phase 4 trial, led by Johns Hopkins University, is studying a new digital stethoscope that uses artificial intelligence to help doctors decide when antibiotics are really needed for children with respiratory infections. By reducing unnecessary antibiotic use, this tool could help protect children from side effects and antibiotic resistance. The study is recruiting 2,500 children in Bangladesh and aims to improve how lung infections are treated in young patients.

Children's Health, Respiratory Inflammation and Short-term Air Pollution

Researchers at Queen Mary University of London are exploring how physical activity versus rest affects breathing in children with asthma who live in areas with high air pollution. This study could provide important information to help families and doctors make better decisions on how much activity is safe on days with poor air quality. The study is currently recruiting children in the United Kingdom and focuses on how pollution impacts asthma symptoms.

COVID-19 Vaccine Response in Chronic Respiratory Conditions

This study from National Jewish Health in the United States is following adults and children with chronic respiratory conditions to understand how well their immune systems respond to COVID-19 vaccines. The goal is to identify ways to improve vaccine protection for people with lung diseases and other health problems. Participants will be followed for 18 months to gather detailed information about their immune response over time.

Effectiveness of the Evaluation and Communication of "Pulmonary Age" as Help for Smoking Cessation

In France, this trial is testing whether telling smokers their "pulmonary age"—a measure comparing their lung health to typical lung function at different ages—can encourage them to quit smoking. This approach aims to provide a personalized and clear message about lung damage to motivate quitting. The study follows adults for one year using visits and phone calls to support smoking cessation efforts.

Swiss Paediatric Airway Cohort

The University of Bern is leading a national study in Switzerland that tracks children and teens with recurring wheezing, coughing, and exercise-related breathing difficulties. By collecting long-term data through questionnaires and clinical visits, researchers hope to better understand these breathing problems and improve diagnosis and treatment. The study involves multiple clinics and aims to help doctors manage respiratory conditions in young patients more effectively.

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