Mental Health & Psychiatry Clinical Trials Update: Week 45, 2026

Published November 6, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

Long-term Maintenance Study of Aripiprazole in the Treatment of Irritability Associated With Autistic Disorder

This completed Phase 4 study involved 215 children with irritability related to autism across multiple U.S. locations. It explored whether continuing treatment with aripiprazole helps delay relapse compared to stopping the medication. The results offer important information for families and caregivers seeking stable, long-term treatment options for managing irritability in children with autism.

Parent-implemented Social Communication Treatment in Preschool Children With Autism Spectrum Disorder

This study from the Chinese University of Hong Kong enrolled 144 preschool children with autism spectrum disorder to test two types of parent-led communication therapies. It aims to determine which approach, group or individual therapy, better supports social communication skills and is cost-effective. The findings may help parents choose the most suitable therapy method to support their child’s development.

The Effectiveness of a Mindfulness Based Program on Short- Form Video Addiction in Adolescents

Conducted in Turkey with 77 adolescent participants, this study evaluated a mindfulness program designed to reduce addiction to short-form videos. If effective, this non-medication approach could provide a helpful tool for young people struggling with excessive video use and its impact on mental health. Results may guide future strategies to address digital addiction in youth.

A Pre-post Study of a Lethal Means Safety Planning Intervention for Youth at Elevated Suicide Risk in the Emergency Department

This upcoming study by the University of Colorado, Denver, plans to enroll 200 teenagers at high risk of suicide. It tests a safety planning intervention focused on firearm safety and involving both teens and caregivers during emergency department visits. This approach aims to reduce suicide risk by promoting safer environments and stronger support systems for vulnerable youth.

A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2)

Currently recruiting in the United States, this trial offers a 9-session online mindfulness program for adolescents aged 12 to 17 who are at risk of mood and anxiety difficulties. The program seeks to help young people manage negative emotions without medication, providing a potentially accessible mental health tool. Follow-up assessments will evaluate the program’s lasting effects on emotional well-being.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.