Mental Health & Psychiatry Clinical Trials Update: Week 44, 2026

Published October 30, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

AI-Based CBT Chatbot for Adolescent Social Anxiety

This study from Central China Normal University is exploring a new way to help teenagers with social anxiety using an artificial intelligence-based chatbot that delivers cognitive behavioral therapy. If successful, this tool could make therapy more accessible by providing support without needing in-person sessions. The trial plans to include 120 adolescents and will check how well the chatbot works one month after treatment, which could offer a convenient option for young people struggling with social anxiety.

Development and Evaluation of a Digital Game Intervention Targeting Children Vulnerable to ADHD

Researchers at The Hong Kong Polytechnic University are testing a digital game designed to help children aged 6 to 12 who show signs of attention deficit hyperactivity disorder or related symptoms. This game aims to improve attention and reduce ADHD symptoms, potentially giving children a fun and easy way to get early support before professional treatment is available. The study includes 100 children and compares the game to another activity over 16 weeks, focusing on whether this approach can help manage attention challenges.

Cognitive and Behavioral Approaches to Reduce Binge Eating and Excess Weight in Adolescents (Online)

Indiana University is conducting an online study to find out which psychological and lifestyle treatments best reduce binge eating and excess weight in teenagers. This research is important because it could provide new options for adolescents dealing with eating disorders and overweight issues outside of traditional in-person care. The remote nature of the trial makes it easier for teens across the United States to participate and access support.

Short, Wordless Animated Storytelling to Promote Mental Health Help-Seeking in Young Adults: A U.S. Online Randomized Controlled Trial

Stanford University is testing whether a brief, wordless animated film can encourage young adults to seek help for mental health concerns. This simple digital intervention targets people aged 18 to 25 and could make it easier for more young adults to feel comfortable reaching out for support. The study involves 2100 participants across the U.S. and measures their attitudes immediately and one week after watching the film.

STRIDE: Stress Reduction in Dementia Caregivers

Massachusetts General Hospital completed a study on a smartphone app designed to reduce stress for caregivers of people with Alzheimer's and related dementias. This app could provide a non-medication way to help caregivers manage emotional distress and improve mindfulness. With 95 participants finishing the trial, the results are now available and may offer new tools for caregiver support.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.