Mental Health & Psychiatry Clinical Trials Update: Week 33, 2026

Published August 14, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

A Clinical Trial Evaluating Fecal Microbiota Transplantation (FMT) in Adolescents With ADHD

This phase 2 study is exploring a new approach for treating adolescents aged 13 to 17 with ADHD by using oral fecal microbiota transplantation, or FMT. If successful, this method could offer a treatment option that works differently from current medications, potentially improving symptoms through changes in gut health. The trial is currently recruiting participants in Canada and focuses on understanding whether this treatment is safe and well tolerated.

Motivational Refinements for Facilitating Reinforcement Schedule Thinning

This trial is testing new improvements to behavioral therapies designed for children with developmental disabilities who show destructive behaviors. The goal is to enhance communication skills that reduce harmful actions and make treatment easier for families to apply consistently. Recruiting in the United States, this study aims to help children develop better functional behaviors through refined motivational strategies.

Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis

This study is evaluating a group program focused on suicide prevention for young people at high risk of psychosis. The program, led by clinicians and peers, is designed to build hope and encourage recovery by teaching suicide prevention strategies and goal setting. Conducted in the United States, it compares this supportive group approach plus standard care to standard care alone, aiming to improve mental health outcomes for participants.

Forging Hopeful Futures to Reduce Youth Violence

This research tests a community-based violence prevention program for adolescents aged 13 to 19 that addresses factors like racial and economic justice. The program offers new ways for young people to develop safer behaviors and coping skills through wellness check-ins and supportive activities. The study is active but not currently recruiting, and it seeks to reduce violence by focusing on social and communication skills in youth.

Efficacy Trial of the CALM Intervention

This trial examines a nurse-delivered behavioral intervention called CALM aimed at children with anxiety disorders. The focus is on reducing anxiety symptoms and improving how children function at school through a straightforward and accessible approach. Based in the United States, the study includes follow-up to see if the benefits last over time, offering hope for easier-to-access anxiety support.

This week’s research highlights show ongoing efforts to develop new treatments and support programs that address mental health challenges in young people. From innovative biological therapies to community and behavioral interventions, these trials represent diverse strategies aiming to improve daily life and long-term outcomes. The coming months will bring more data that could shape future care options.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.