Mental Health & Psychiatry Clinical Trials Update: Week 32, 2026

Published August 7, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

Mindfulness-Assisted Psychedelic Therapy

This Phase 2 trial from the University of Southern California is exploring a combination of psilocybin, a psychedelic compound, with mindfulness training in healthy adults. The study aims to see if mindfulness can boost the positive effects of psilocybin on reducing stress and improving overall mental wellness. With follow-ups extending up to one year, this research could open the door to new ways of supporting mental health through combined therapy approaches.

Emotion Regulation for Middle Schoolers

Researchers at the University of Oregon are testing a digital program designed to improve emotional skills in middle school students and their teachers. By strengthening emotion regulation, the program hopes to shield young adolescents from risky behaviors and future mental health challenges. The study will monitor participants over four months to understand how this approach impacts emotional health in everyday school life.

COPEWeb Training for Providers

The VA Office of Research and Development is evaluating a new web-based training for healthcare providers treating veterans with post-traumatic stress disorder (PTSD) and substance use disorders. By increasing the number of trained providers, this program aims to expand access to effective therapies for veterans facing these challenges. The study's large enrollment goal reflects the importance of making proven treatments more widely available.

Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)

This completed Phase 2 study from Yale University looked at using the medication lisdexamfetamine to help people who experience loss-of-control eating after weight loss surgery. The trial focused on patients who did not benefit from earlier treatments, seeking new options to improve eating habits and post-surgery outcomes. Results from this study may guide future care for individuals struggling with eating behaviors following bariatric surgery.

Developing and Testing a Brief, Personalized Intervention for Suicidal Thoughts and Behaviors

The University of California, San Diego is conducting a trial testing a brief, personalized psychological intervention aimed at reducing suicidal thoughts and emotional distress. Using data collected through smartphone surveys, the therapy adapts to each person’s needs. Recruiting university students, this research could lead to more tailored and accessible support for those at risk of suicide.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.