Mental Health & Psychiatry Clinical Trials Update: Week 23, 2026

Published June 5, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

Randomized Controlled Trial of a Family-focused Intervention for Caregivers and Young Adolescents (Phase 3 of FLOURISH)

This study is testing a family-focused behavioral program for adolescents aged 10 to 14 who have emotional and behavioral challenges, along with their caregivers. By involving the whole family, the program aims to improve mental health and family relationships, offering support beyond medication or traditional therapy. The trial is recruiting 1,280 participants in Moldova and North Macedonia, which could help many families find new ways to cope together.

Future Leaders Program: Testing a Youth Leadership, Engagement, and Mindfulness Program

This trial explores a program designed to promote leadership skills, engagement, and mindfulness among adolescents. By supporting mental health and well-being through these activities, it may provide young people with practical tools to manage emotional and behavioral issues. Currently recruiting over 500 participants in the United States, this program could become an accessible option for improving youth mental wellness.

Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention

The iCHART study focuses on adolescents at risk of suicide and depression, testing an integrated care approach that combines referrals and safety planning. This method aims to enhance how mental health care is delivered to teens, potentially lowering the risk of suicidal events. With 900 teens being recruited in the United States, the findings could shape future strategies to better protect vulnerable young people.

Reducing Children's Racial Biases Via a Parent-Led Intervention

This completed trial examined a program led by parents to reduce racial biases in children from White families. If effective, the intervention could equip families with tools to address and lessen racial bias early in childhood. The study involved 704 participants in the United States, and its results may guide new approaches to fostering inclusivity from a young age.

Improving Care, Accelerating Recovery and Education

The I-CARE trial is testing a digital program designed to reduce suicidal thoughts and emotional distress in children during hospital stays while they wait for mental health treatment. This modular program could offer a supportive and accessible way to help young patients through critical times. The study is currently active and recruiting at two U.S. locations, aiming to improve care during vulnerable periods.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.