Orthopedics & Musculoskeletal Clinical Trials Update: Week 32, 2026

Published August 7, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

iFuse TORQ for the Treatment of Sacroiliac Joint Dysfunction

This Phase 4 trial tests the iFuse TORQ implant system for adults with sacroiliac joint dysfunction, a condition that causes pain in the lower back and pelvis. The implant is designed to fuse the sacroiliac joint using a minimally invasive procedure, aiming to reduce pain and improve how well patients can move. With 110 participants across 14 sites in the United States, this study could provide important information on a less invasive treatment option for people struggling with sacroiliac joint pain.

Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill Quantity

This study is exploring new ways to manage pain after surgery on the arms or hands by testing lower doses of opioids combined with gabapentin, a non-opioid medication. The goal is to help patients control pain while reducing the risk of opioid dependence or side effects. Currently recruiting 260 participants in the United States, this trial could influence safer pain relief methods following upper limb surgeries.

Autologous Fat Grafting for the Treatment of Chronic Tendinopathy

This study examines whether injecting a person’s own concentrated fat tissue into a damaged tendon can relieve chronic tendon pain that has not improved with other treatments. If successful, this one-time procedure might offer a new, less invasive option for patients dealing with persistent tendon problems. The trial is recruiting at one site in the United States and will follow participants for about one year to assess long-term effects.

Core Stabilization Exercise Therapy in Chronic Lower Back Pain Management in Community Dwelling Older Adults

This research is testing a 16-session core exercise program aimed at older adults living in the community who suffer from long-term lower back pain. The exercises focus on strengthening the muscles around the spine, which may help reduce pain and improve daily function without the need for medication. Conducted in Hong Kong, this program could provide a valuable non-drug option for managing back pain in people aged 40 to 80.

Geriatric Trauma Care Program for Living Alone Older Adults With Injuries

This study is developing a specialized care program for older adults who live alone and have experienced injuries. It looks at improvements in pain, physical function, depression, loneliness, and quality of life. Recruiting 90 participants in Taiwan, the trial aims to address multiple challenges faced by this vulnerable group and improve their overall well-being after trauma.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.