Orthopedics & Musculoskeletal Clinical Trials Update: Week 15, 2026

Published April 10, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert

Perioperative Mental Health in Orthopedic Surgery

This completed study from Washington University School of Medicine focused on reducing depression and anxiety in older adults undergoing orthopedic surgery. By combining behavioral therapy with medication, the research aimed to support patients' mental health during their recovery. The results could lead to new approaches that help improve emotional well-being alongside physical healing after surgery.

MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)

Currently recruiting in the United States and Canada, this trial compares two common surgeries for older adults with femoral neck fractures—hip arthroplasty and internal fixation. The goal is to determine which procedure leads to faster recovery and better quality of life. This information may help patients and doctors choose the surgery that best supports healing and daily function after a hip fracture.

Effectiveness of RPT With Elastic Band in Tx of Sarcopenia in LTCFs

Conducted in rural long-term care facilities in Taiwan, this study tests a simple exercise program using elastic bands to strengthen muscles in older adults with sarcopenia, or muscle loss. The 12-week program involves twice-weekly sessions and aims to improve muscle health with minimal equipment. If successful, this approach could offer an accessible way to help residents maintain strength and independence.

Healthy Living After Knee Replacement

This study from the University of South Carolina is testing a weight loss and physical activity program for adults after knee replacement surgery. The program aims to reduce pain and improve physical function by encouraging healthier habits. With 182 participants, the trial seeks to find better ways to support recovery and long-term health following knee replacement.

Brace Monitoring for Adolescent Idiopathic Scoliosis (AIS)

Recruiting adolescents in the United States, this trial examines a new device and smartphone app designed to track how often and how well patients wear their spinal braces. Better monitoring could help doctors adjust treatment and encourage consistent use, which may improve the effectiveness of braces for scoliosis. This technology offers a modern way to support young patients through their treatment.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.