Eye Disease & Ophthalmology Clinical Trials Update: Week 19, 2026

Published May 8, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

This Phase 4 trial is exploring whether using atropine eye drops at night can delay the start of nearsightedness in children. If it works, this treatment might help slow down vision worsening for kids who are at risk of developing myopia. The study is currently recruiting participants in the United States, and results are expected after two years of treatment.

Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity

This Phase 2 trial is testing oral propranolol as a way to prevent severe retinopathy of prematurity, a serious eye condition affecting extremely premature infants. A successful outcome could mean a simpler and less invasive treatment to reduce the risk of vision loss in these vulnerable babies. The study is recruiting 276 infants across Germany, Switzerland, and Turkey.

3D Movie Viewing vs Occlusion for Treating Amblyopia in Children

This study is investigating whether watching 3D movies alongside standard patching therapy improves vision in children with amblyopia, also known as lazy eye. If effective, this could offer a more engaging treatment that may help improve depth perception and eye alignment in children aged 4 to 14. The trial is currently recruiting and aims to inform future therapy options.

Control of Myopia Using Novel Spectacle Lens Designs

This ongoing study is testing new spectacle lenses designed to slow the progression of juvenile myopia in children. If successful, these lenses could provide a non-invasive way to help manage worsening vision in young patients. The trial is taking place at multiple sites in the United States and Canada and is enrolling children diagnosed with myopia.

CYPRESS Efficacy and Safety Study Extension

This study evaluates a new type of spectacle lens aimed at slowing juvenile myopia progression. If the results are positive, this could offer children an easier and safer alternative to invasive treatments for managing nearsightedness. The trial is ongoing in the US and Canada with 200 participants, and results are expected after 36 months.

This week, research in eye disease and ophthalmology continues to focus on improving treatments for common childhood vision problems such as myopia and amblyopia, as well as addressing serious conditions affecting premature infants. These studies highlight ongoing efforts to find safer, more effective, and less invasive options to protect and improve vision from an early age.

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