Eye Disease & Ophthalmology Clinical Trials Update: Week 15, 2026

Published April 10, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert

Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Diabetic Macular Edema

This Phase 3 trial is comparing BAT5906 injections to Lucentis for people with diabetic macular edema, a common cause of vision loss in diabetes. The study is testing whether BAT5906 can be as effective or better than the current standard treatment, potentially offering patients another option to help improve their vision. Over 400 participants in China are involved, with results expected after one year of treatment.

Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery

This study is looking at whether a nasal spray medication, dexmedetomidine, can safely control blood pressure in older adults with high blood pressure during cataract surgery. If successful, it could make the surgery safer by reducing blood pressure-related risks without complicated procedures. The trial is recruiting patients aged 65 and older in Egypt who have controlled hypertension.

This is a Phase II/III, Multicenter, Randomized, Active Comparator-controlled, Double-masked, Parallel-group, 96 Week Study to Investigate the Efficacy, Safety, Durability, and Pharmacokinetics of OCUL101 Administered to Patients With Neovascular AMD. There Will be Two Parts, Part A and Part B.

This upcoming Phase 2/3 trial will test OCUL101, a new treatment designed to target two pathways involved in neovascular age-related macular degeneration, a leading cause of vision loss in older adults. The study aims to see if this dual-action treatment is safe and effective over nearly two years compared to existing options. While not yet recruiting, this trial could lead to a new approach for managing this serious eye condition.

Video Treatment for Amblyopia

This study is exploring a video-based therapy as an alternative to traditional eye patching for young children with amblyopia, often called lazy eye. If the video treatment proves effective, it may offer a more engaging and easier way for children to improve vision in the weaker eye. The trial is currently recruiting 44 children in the United States.

Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center

This research is testing if an educational video can help patients with diabetic retinopathy better understand their condition and the importance of follow-up care. Improved knowledge may encourage patients to manage their eye health more effectively, potentially reducing the risk of vision loss. The study is recruiting adults with diabetes at a single site in the United States.

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