Kidney Disease & Nephrology Clinical Trials Update: Week 25, 2026

Published June 19, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

Pivotal Study of the Velocity™ pAVF System

This study is testing a new, less invasive way to create access for dialysis in adults with kidney failure. The Velocity pAVF System may reduce the need for traditional surgery, which could mean shorter recovery times and fewer complications. Patients in this study are being followed for up to five years across several centers in the United States, offering valuable long-term information on this approach.

Phentermine/Topiramate for Uric Acid Stones

This Phase 2 trial explored a combination medication for obese and diabetic patients who have uric acid kidney stones. Results from the completed study suggest this treatment might reduce the size of kidney stones and help better manage related health issues. Conducted at a single U.S. site, these findings could lead to new options for patients struggling with stones linked to obesity and diabetes.

Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD: A Pilot Randomized Open-Label Trial

This upcoming study aims to test whether low-dose colchicine can lower inflammation in adults with stage 3 chronic kidney disease. Reducing inflammation may improve blood vessel and bone health, which are often affected by kidney disease. Although not yet recruiting, this 12-month pilot trial could introduce new ways to reduce cardiovascular risks in kidney patients.

A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)

This Phase 3 study focuses on children aged 0 to 9 who have severe kidney disease and a condition called secondary hyperparathyroidism. By testing paricalcitol oral solution, the trial seeks safer and more effective treatments for young patients on dialysis. Conducted across multiple sites in the U.S. and Puerto Rico, the study lasted 24 weeks and provides important data for pediatric kidney care.

Music Intervention for Dialysis Patients

This study looked at how live and recorded music may help reduce pain and anxiety during dialysis. With 102 participants in Singapore, the trial explored a simple, drug-free way to improve the dialysis experience. If effective, music interventions could become a valuable part of supportive care for patients undergoing regular dialysis treatments.

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