Kidney Disease & Nephrology Clinical Trials Update: Week 16, 2026

Published April 17, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert

Pentoxifylline in Diabetic Kidney Disease

This Phase 4 study is examining whether the drug pentoxifylline can slow down kidney damage in patients with diabetic kidney disease. The research, conducted across 40 VA hospitals in the United States, aims to find a treatment that may delay worsening kidney function and reduce the risk of death. While the study is active, it is not currently recruiting new participants, but its findings could offer hope for those living with this condition.

Lipid Management in Renal Transplant Recipients Using Evolocumab

This study focuses on kidney transplant patients who have high cholesterol levels and tests a drug called evolocumab, which may be a safer alternative to statins. Statins can cause side effects in transplant recipients, so finding another effective treatment is important. The trial included 81 patients at one US site and has completed results, providing valuable insights for managing cholesterol in this group.

Kidney Precision Medicine Project

This ongoing research uses advanced biopsy and imaging techniques to better understand different types of kidney disease, including both acute and chronic forms. By identifying the specific characteristics of each patient’s kidney condition, the study hopes to pave the way for more personalized and effective treatments in the future. It is currently recruiting adults with various stages of kidney injury or disease at multiple locations in the United States.

NAD Augmentation in Diabetes Kidney Disease

This Phase 2 trial is testing an oral drug called NMN to see if it can improve kidney health in people with type 2 diabetes. The study aims to reduce kidney damage and improve overall outcomes by potentially offering a new treatment option. Recruitment is underway in the United States, and the trial will assess kidney function changes over a six-month period.

Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial

This trial is exploring a new ultrasound system designed to evaluate the maturation of arteriovenous fistulas in patients with diabetes and end stage renal disease. A fistula is a key access point for dialysis, and faster maturation could mean quicker and better treatment access. The study is recruiting adults with kidney failure at multiple sites across the United States.

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