Kidney Disease & Nephrology Clinical Trials Update: Week 15, 2026

Published April 10, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert

Shingrix in Renal Transplant Recipients

This Phase 3 study led by the University of Colorado, Denver is examining the safety and immune response of the Shingrix vaccine in adults with kidney failure who are waiting for or have received a kidney transplant. The trial is exploring whether giving an additional dose of the vaccine after transplant can better protect these patients from shingles, a painful viral infection. This research is important because people with kidney failure and transplant recipients are more vulnerable to infections like shingles, and improved vaccine strategies could enhance their health and quality of life.

The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients With Diabetic Kidney Disease

This Phase 2 trial in Denmark is testing a new drug called R3R01 in adults with diabetic kidney disease, focusing on its ability to reduce protein in the urine. Protein leakage can signal worsening kidney damage, so lowering it may help protect kidney function and better manage blood pressure. If successful, this treatment could offer a new option for people living with diabetes-related kidney problems, a common cause of kidney failure worldwide.

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

This Phase 2 trial by Hoffmann-La Roche is investigating the drug obinutuzumab in children and teenagers who have active lupus nephritis, a serious kidney inflammation caused by lupus. The study aims to find out if the medication is safe and effective in this younger group. Results could lead to improved treatment options for young patients with lupus nephritis, potentially reducing kidney damage and improving long-term health outcomes.

SLIT ABS: Study on Patients With Autoimmune Podocytopathy

This international study is focused on children with nephrotic syndrome, a condition causing swelling and kidney issues. Researchers are testing new ways to detect specific autoantibodies in the blood and kidney tissue, which may help identify why some patients do not respond well to current treatments. Better understanding of these antibodies could lead to more personalized and effective therapies for children facing this challenging kidney disorder.

Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength

This study from the VA Office of Research and Development is looking at exercise programs for older adults with chronic kidney disease who have experienced muscle weakness after leaving the hospital. The goal is to improve muscle strength and overall physical ability, helping patients recover and maintain independence. This research addresses an important aspect of kidney disease care that goes beyond the kidneys themselves, focusing on overall health and quality of life.

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