Immunology Clinical Trials Update: Week 14, 2026

Published April 3, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert

Revealing Protective Immunity to Influenza Using Systems Immunology

This completed study by Emory University explored how the immune system responds to a nasal spray flu vaccine, especially focusing on why it seems to work better in children than adults. Understanding these differences could help researchers improve flu vaccines for people of all ages, potentially making flu prevention more effective in the future.

UKK-0018 is an Immunotherapeutic for Treatment of Peanut Allergies

This Phase 1 trial in Australia and New Zealand is testing a new injection treatment called UKK-0018 for people with peanut allergies. The goal is to train the immune system to better tolerate peanuts and reduce severe allergic reactions. If successful, this could offer a new option to help manage peanut allergies safely.

Evaluation of the Safety and Efficacy of SALI-10 Probiotic Lozenges

Ostia Sciences is conducting a study in Canada to see if SALI-10 probiotic lozenges can reduce gum inflammation and bad breath caused by gingivitis. People use the lozenges twice daily for four weeks. This treatment might provide a natural way to improve oral health by balancing bacteria in the mouth.

Natural History and Genetics of Food Allergy and Related Conditions

The National Institute of Allergy and Infectious Diseases is running a long-term study in the United States to better understand food allergies and related conditions like eczema and eosinophilic esophagitis. By studying people from ages 2 to 99, this research hopes to find ways to predict and manage these allergic diseases more effectively over time.

Hematopoietic Stem Cells Transplantation in Children With Combined Immunodeficiency (CID)

This Phase 2 trial in France tested a new stem cell transplant approach for children with combined immunodeficiency, a serious immune disorder. The aim was to reduce dangerous side effects while keeping the immune system strong after transplant. This research could lead to safer and more successful treatments for children facing this condition.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.