Women's Health & Gynecology Clinical Trials Update: Week 45, 2026

Published November 6, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

Statin Intervention for Severe Early-Onset Placental Insufficiency. (STATIN-PRE Trial)

This Phase 2 trial is testing whether daily pravastatin can help pregnant women who have preeclampsia or fetal growth restriction caused by problems with the placenta. If the treatment works, it might safely extend pregnancy and improve health for both mothers and their babies. The study is currently recruiting women in Spain between 24 and just under 30 weeks of pregnancy, with a goal of including 154 participants.

The Dutch STRIDER (Sildenafil TheRapy In Dismal Prognosis Early-onset Fetal Growth Restriction)

This trial explores the use of sildenafil tablets for women experiencing severe early-onset fetal growth restriction, a condition where the baby is not growing properly in the womb. The study aims to increase healthy births and survival rates when few treatment options exist. More than 200 women have participated across the Netherlands, focusing on pregnancies between 20 and 30 weeks.

Optimizing Preeclampsia Postpartum With Point-of-care Ultrasound

This Phase 4 study is looking at how bedside ultrasound combined with diuretic medication can improve care for women after childbirth who have preeclampsia, a serious condition involving high blood pressure. The goal is to help doctors better manage blood pressure after delivery, possibly reducing the need for medications and hospital visits. Recruitment is open in the United States for 96 participants.

Tranexamic Acid to Prevent Heavy Bleeding After Childbirth in Women at Higher Risk

This large Phase 3 trial tests whether an injection of tranexamic acid can lower the risk of heavy bleeding after childbirth in women who are more likely to experience this problem. Reducing heavy bleeding can save lives and improve recovery after delivery. The study is recruiting up to 40,000 women in Tanzania, making it one of the largest trials in postpartum care.

Preeclampsia Intervention Netherlands

This Phase 3 trial is evaluating metformin as a treatment to safely prolong pregnancy in women with preterm preeclampsia, which occurs before 37 weeks of gestation. Successfully delaying early delivery might reduce risks for both mother and baby. The study is enrolling about 180 participants in the Netherlands.

This week shows promising progress in managing serious pregnancy complications like preeclampsia and fetal growth restriction. Several trials are testing treatments that could extend pregnancy safely or reduce risks after childbirth. Ongoing research like this is crucial to improving health outcomes for women and their babies worldwide.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.