Women's Health & Gynecology Clinical Trials Update: Week 44, 2026

Published October 30, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.

HB0025-C-0301: A Study to Investigate HB0025 Combined With Chemotherapy as First-Line Treatment for Advanced or Recurrent MMR-proficient Endometrial Cancer

This Phase III trial is exploring whether adding HB0025 to chemotherapy can improve outcomes for patients with advanced or recurrent endometrial cancer that is MMR-proficient. If successful, this treatment could help delay disease progression better than chemotherapy alone. The study is recruiting in China and aims to include around 333 participants.

Ferric Derisomaltose and Outcomes in the Recovery of Gynecologic Oncology: ERAS (Enhanced Recovery After Surgery)

This Phase III trial is testing intravenous ferric derisomaltose to treat iron-deficiency anemia before gynecologic cancer surgery. By improving iron levels ahead of surgery, the treatment might reduce the need for blood transfusions and decrease complications during and after the operation. The study is ongoing in Canada and involves adult patients undergoing surgery for gynecologic cancers.

A Preliminary Exploratory Study of Cadonilimab Combined With Progestin for Fertility-Sparing Treatment in Early Endometrial Cancer

This Phase II study is investigating a new approach for women with early-stage endometrial cancer who wish to preserve their fertility. It combines cadonilimab, an immune therapy, with progestin to provide an alternative for those who do not respond well to standard hormone treatment. The trial plans to enroll a small group of about 10 participants and is still preparing to start recruiting.

Healthy for my Baby - RCT of a Lifestyle Intervention for Overweight Women in Preconception

This study is testing a lifestyle program that uses coaching and a mobile app to support overweight women and their partners before pregnancy. The goal is to encourage healthier habits that may reduce pregnancy complications related to weight. Conducted in Canada, the study includes 68 participants and focuses on improving diet and overall pregnancy outcomes.

Methylation Profiling in Self-samples for Identification of (Epi)Genetic Biomarkers for Gynecological Cancers

This study is exploring a new, less invasive way to detect gynecological cancers by analyzing self-collected urine and vaginal samples. It aims to identify markers that could help diagnose cancers like ovarian and endometrial cancer earlier. The trial is recruiting women in Belgium who have symptoms like postmenopausal bleeding or are at higher risk for these cancers.

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