Women's Health & Gynecology Clinical Trials Update: Week 15, 2026

Published April 10, 2026 — 5 trials covered

By Victor Lafforgue, Founder of TrialsAlert

Levonorgestrel 52 mg IUD for Emergency Contraception and Same-Day Start

This study is testing a levonorgestrel 52 mg intrauterine device (IUD) as an option for emergency contraception and for starting contraception on the same day. If successful, this could offer people a reliable and convenient way to prevent pregnancy after unprotected sex or to begin contraception immediately. The trial is currently recruiting at eight Planned Parenthood locations across the United States and is following participants for one month after IUD placement.

Azithromycin Prophylaxis for PRElabor Cesarean Delivery Trial

This phase 3 trial is exploring whether giving the antibiotic azithromycin to pregnant women before scheduled cesarean deliveries can reduce the risk of infections after birth. If effective, this approach could improve recovery and health outcomes for mothers by lowering infection rates following cesarean sections. The study is recruiting up to 8,000 participants across the United States and aims to inform future standards of care.

The Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents

This research evaluates the safety and effectiveness of Bonjesta for treating nausea and vomiting during pregnancy specifically in adolescents aged 12 to 17. If the results are positive, it may provide a new treatment option to help young pregnant patients manage common pregnancy symptoms more comfortably. The study is recruiting in the United States and focuses on improving care for this age group.

Investigations of Reproductive Cancers in Women

This study is testing a new non-invasive diagnostic test aimed at detecting uterine cancer in women aged 45 and older who experience abnormal or postmenopausal bleeding. If successful, this test could reduce the need for invasive procedures, making diagnosis easier and safer. The trial is recruiting 4,500 participants in the United States and hopes to improve cancer detection methods.

Pragmatic Randomized Clinical Trial to Limit Weight Gain in Pregnancy and Prevent Obesity

This trial examines a remote health coaching program designed to help pregnant women limit weight gain during pregnancy and reduce obesity risk for themselves and their children. The program offers behavioral support that could be widely accessible and improve health outcomes for both mothers and babies. The study recently completed with 534 participants at Johns Hopkins prenatal clinics in the United States.

TrialsAlert subscribers received the full impact-classified briefing and doctor-ready report this week. Get weekly briefings at trialsalert.com.