Digestive Health & Gastroenterology Clinical Trials Update: Week 45, 2026
Published November 6, 2026 — 5 trials covered
By Victor Lafforgue, Founder of TrialsAlert. Blog posts are AI-drafted from ClinicalTrials.gov source data and reviewed by the editorial team. See our editorial policy for details.
An Open Label Phase 2 Study of Total Neoadjuvant Therapy (TNT) Consisting of FLOT With Pembrolizumab and Short Radiation for Patients With Locally Advanced Gastroesophageal Junction Adenocarcinoma
This Phase 2 trial explores a combination of chemotherapy, immunotherapy, and radiation for people with locally advanced cancer at the junction of the stomach and esophagus. The goal is to improve treatment results and help doctors decide whether surgery or preserving the organ is best. This study is currently recruiting in Japan and aims to provide new options that may lead to better outcomes for patients facing this challenging cancer.
A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis
This Phase 2 trial tested the drug CIN-102 in adults with diabetic gastroparesis, a condition where the stomach empties too slowly and causes symptoms like nausea and vomiting. Although the study has finished enrolling over 380 participants across the United States, results are not yet available. If CIN-102 proves effective, it could become a helpful new treatment to ease symptoms and improve quality of life for people living with this condition.
Maternal Probiotic Intervention to Improve Gut Health-Trial II-Pakistan
This Phase 2 trial is studying whether giving pregnant women a probiotic treatment combined with oral vancomycin can improve gut health and reduce inflammation linked to childhood stunting. The study is recruiting women in early pregnancy in Pakistan and focuses on environmental enteric dysfunction, which can affect how children grow. Success in this trial might lead to new ways to support healthier growth and development in children by improving their mothers’ gut health during pregnancy.
Multi-center Prospective Validation of Real-Time AI-EGGIM System
This study is testing a new artificial intelligence system designed to help doctors better identify gastric intestinal metaplasia, a condition that can lead to stomach cancer. By improving the detection of this precancerous change during routine endoscopy, the system could help catch risks earlier and guide more careful monitoring. The trial is recruiting patients in China and could improve how stomach cancer risk is managed in the future.
TEAS for Gastrectomy Recovery
This trial is exploring a non-invasive electrical stimulation treatment to aid recovery after stomach cancer surgery. The treatment aims to reduce pain and speed up healing without needles or drugs. Recruiting adults in China, this study could offer a simpler way to improve comfort and reduce reliance on pain medicines during the critical recovery period after surgery.
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